SEARCH RESULTS FOR: Cervical-Insufficiency

Cervical Insufficiency

Cervical Insufficiency: Pathogenesis and clinical findings Cervical lacerations Cervical loop Cone biopsy electrosurgical procedure excision procedure Cervical procedures Post-procedure cervical re-modelling ↓ Structural collagen in extracellular matrix Opened cervix allows for ↑ voiding of vaginal skin cells, bacteria, mucous and fluid Fetal head moves lower into pelvis, exerting pressure on pelvic ligaments Hysteroscopy dilatation and curettage Antepartum Sterile intra-amniotic infection inflammation Inflammatory cascade within cervix ↑ Local myometrial and cervical prostaglandins/ cytokines ↑ Collagenase and leukocyte elastase increases break down of collagen Congenital abnormality of collagen synthesis Ex. Ehler-Danlos syndrome ↑ Vaginal discharge Change in color of vaginal discharge Braxton-Hicks-like contractions Menstrual-like cramps Back ache ↓ Cervical tensile strength and rigidity Cervical Insufficiency Spontaneous dilation and thinning of cervix Unknown cause Prolapsed fetal membranes Second trimester loss or preterm birth Risk of recurrent second trimester loss or preterm birth Authors: Kiera Pajunen Reviewers: Ran (Marissa) Zhang Brianna Ghali Ingrid Kristensen* * MD at time of publication Debris seen in amniotic fluid on U/S Short cervix (<2.5cm on trans-vaginal ultrasound) Legend: Pathophysiology Mechanism Sign/Symptom/Lab Finding Complications Published July 5, 2022 on www.thecalgaryguide.com